Query Result:

Summary: help

Your query was: Q16665    
1
826

Domain annotation: [ InterPro ]

Colors:    Query |  Sequence |  Structures |  Models  |  Domains   |    

Q16665 HIF1A_HUMAN ; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8; Homo sapiens (Human).

  

Models:

Model
 
Rel.
 
Provider
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Type

Templates
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%Seq id
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Sel.
[Show] reliability_1
SWISSMODEL
SC 3f1pA
75% 237 345
[Show] reliability_3
SWISSMODEL
SC 3gecA
29% 220 374
[Show] reliability_3
NESG
TC 3lyxA
22% 249 333
[Show] reliability_3
NESG
TC 3mjqA
13% 247 337
[Show] reliability_1
MODBASE
SC 4h6jA
99% 238 343

Experimental Structures:

PDB Description %Seq Id from - to Sel.
4h6jIdentification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
99 238-348   
1h2mFACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
100 775-826   
1l8cSTRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE
100 776-826   
2ilmFactor Inhibiting HIF-1 Alpha D201A Mutant in Complex with FE(II), Alpha-Ketoglutarate and HIF-1 Alpha 35mer
100 786-826   
1h2lFACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
100 786-826   
1h2kFACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH HIF-1 ALPHA FRAGMENT PEPTIDE
100 786-826   
1l3eNMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex
100 786-826   
1lqbCrystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex
100 549-582   

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